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Intralipid (CAS 68890-65-3) - chemical structure image

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Intralipid (CAS 68890-65-3) - chemical structure image
Intralipid: sc-215182

Intralipid (CAS 68890-65-3)

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Alternate Names:
Phospholipid stabilized soybean oil
Application:
Intralipid is a solubilization agent shown invitro to supply essentially fatty acids for cells
CAS Number:
68890-65-3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Intralipid is a solubilization agent shown in vitro to supply essential fatty acids for cells. It is an emulsion made from soybean oil, phospholipids, glycerin, and water. Intralipid is commonly used as a component of parenteral nutrition regimens.

References:

  1. Absorption of Intralipid and interferences from nutrients infused into the peritoneal cavity of the rat.  |  Mahedero, G., et al. 1992. Am J Surg. 164: 45-50. PMID: 1626606
  2. Loss of Intralipid®- but not sevoflurane-mediated cardioprotection in early type-2 diabetic hearts of fructose-fed rats: importance of ROS signaling.  |  Lou, PH., et al. 2014. PLoS One. 9: e104971. PMID: 25127027
  3. Efficacy of resuscitation with Intralipid in a levobupivacaine-induced cardiac arrest model.  |  Karcioğlu, M., et al. 2014. Turk J Med Sci. 44: 330-6. PMID: 25536745
  4. Surface layering properties of Intralipid phantoms.  |  Bodenschatz, N., et al. 2015. Phys Med Biol. 60: 1171-83. PMID: 25590919
  5. Intralipid™ administration attenuates the hypotensive effects of acute intravenous amiodarone overdose in a swine model.  |  Xanthos, T., et al. 2016. Am J Emerg Med. 34: 1389-93. PMID: 27131633
  6. Protective Effects of Intralipid and Caffeic Acid Phenyl Esther (CAPE) on Neurotoxicity Induced by Ethanol in Rats.  |  Basarslan, SK., et al. 2017. Turk Neurosurg. 27: 66-73. PMID: 27593743
  7. Intralipid protects the heart in late pregnancy against ischemia/reperfusion injury via Caveolin2/STAT3/GSK-3 beta pathway.  |  Li, J., et al. 2017. J Mol Cell Cardiol. 102: 108-116. PMID: 27847332
  8. Therapeutic effects of intralipid and medialipid emulsionsin a rat model of verapamil toxicity.  |  Akgün Şahin, F., et al. 2016. Turk J Med Sci. 46: 1568-1572. PMID: 27966330
  9. Low dose Intralipid resuscitation improves survival compared to ClinOleic in propranolol overdose in rats.  |  Macala, KF., et al. 2018. PLoS One. 13: e0202871. PMID: 30161186
  10. Effect of intralipid administration on calcium therapy in verapamil toxicity.  |  Ozen, SB., et al. 2019. Bratisl Lek Listy. 120: 789-793. PMID: 31663356
  11. Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System.  |  Chen, YJ., et al. 2020. Sci Rep. 10: 2838. PMID: 32071352
  12. Diabetic Rat Hearts Show More Favorable Metabolic Adaptation to Omegaven Containing High Amounts of n3 Fatty Acids Than Intralipid Containing n6 Fatty Acids.  |  Lucchinetti, E., et al. 2020. Anesth Analg. 131: 943-954. PMID: 32398434
  13. Intralipid and haemodialysis in caffeine overdose.  |  Harsten, R., et al. 2020. BMJ Case Rep. 13: PMID: 32414776
  14. Unraveling the role of Intralipid in suppressing off-target delivery and augmenting the therapeutic effects of anticancer nanomedicines.  |  Islam, R., et al. 2021. Acta Biomater. 126: 372-383. PMID: 33774199
  15. An experimental and numerical modelling investigation of the optical properties of Intralipid using deep Raman spectroscopy.  |  Moran, LJ., et al. 2021. Analyst. 146: 7601-7610. PMID: 34783335

Hi, can you estimate the calories per mL of this Intralipid? Thanks!

Asked by: mav2
Thank you for your question. This parameter of the compound is not determined.
Answered by: Tech Support Europe
Date published: 2020-11-23

What's the shelf life of this intralipid?

Asked by: beaver
For accurate shelf life information regarding our chemical products, please contact our Technical Service group.
Answered by: Tech Service
Date published: 2019-02-12

What is the shipping temperature of this product?

Asked by: hawkeye11
This chemical, Intralipid (CAS 68890-65-3), is shipped on blue ice.
Answered by: Chemical Support 1
Date published: 2018-07-07
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Rated 5 out of 5 by CJ from Ok Ok, SH. et al. (PubMed 26273653) investigated the effects of Lipofundin MCT/LCT and Intralipid on acetylcholine-induced nitric oxide- (NO-) mediated relaxation in rat aorta to determine which lipid emulsion (LE) was more potent in terms of inhibition of NO-induced relaxation. -SCBT Publication Review
Date published: 2015-04-27
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Intralipid | CAS 68890-65-3 is rated 5.0 out of 5 by 1.
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