although CYP2E1 also plays a role in the pro-cess. ADH is found primarily in the liver, but is also found in theoral mucosa and even in the oral microbiota. 12,13 In a second step,acetaldehyde is oxidized to acetate by ALDH 14 (Fig. 1).There are several hypotheses on the carcinogenic action of alco-hol. On the one hand, alcohol could act as a carcin...