HPLCvocabulary- 5.0共36页
- 简介:此文档是关于HPLCvocabulary的doc文档,编号为132225299,其中主题是关于论文 、论文指导/设计的内容展示: 高效液相色谱HPLC词汇中英文对照22008092820:19填料packingmateial停流进样涂层毛细管coatedcapillay拖尾峰tailingpeak拖尾因子taili
Association of the Asp312Asn and Lys751 Gln polymorphisms in the XPD gene with the risk of non-Hodgkin's lymphoma:evidence from a meta-analysis- 5.0共7页
- Polymorphisms in DNA repair genes may alter DNA repair capacity and,consequently,lead to genetic instability and carcinogenesis.Several studies have investigated the association of the Asp312 Asn and Lys751 Gln polymorphisms in the xeroderma pigmentosum complementation group D {XPD) gene with the risk of non-Hodgkin's lymphoma(NHL),but the conclusions have been inconsistent.Therefore,we performed this meta-analysis to more precisely estimate these relationships.A systematic literature search was performed using the PubMed,Embase,and Chinese Biomedical(CBM) databases.Ultimately,6 studies of Asp312 Asn,comprising 3,095 cases and 3,306 controls,and 7studies of Lys751 Gln,consisting of 3,249 cases and 3,676 controls,were included.Pooled odds ratios(ORs) and 95%confidence intervals(CIs) were calculated to assess the strength of each association.Overall,no association was observed between the Asp312 Asn polymorphism and NHL risk(homozygous:OR = 1.11,95%CI = 0.94-1.32;heterozygous:OR = 1.00,95%CI = 0.89-1.11;recessive:OR = 1.12,95%CI = 0.95-1.31;dominant:OR = 1.02,95%CI = 0.92-1.13;and allele comparison:OR = 1.04,95%CI = 0.96-1.12) or between the Lys751 Gln polymorphism and NHL risk(homozygous:OR = 0.97,95%CI = 0.83-1.15;heterozygous:OR = 0.96,95%CI = 0.86-1.06;recessive:OR = 1.00,95%CI = 0.86-1.16;dominant:OR = 0.96,95%CI = 0.87-1.06;and allele comparison:OR = 0.98,95%CI = 0.91-1.05).Furthermore,subgroup analyses did not reveal any association between these polymorphisms and ethnicity,the source of the controls,or the NHL subtype.These results indicated that neither the Asp312 Asn nor Lys751 Gln XPD polymorphism was related to NHL risk.Large and well-designed prospective studies are required to confirm this finding.
- A new species of the genus Theloderma Tschudi, 1838 (Amphibia: Anura: Rhacophoridae) from Tay Nguyen Plateau, central Vietnam
- 5.0共27页
- A new species of small tree frog from a primary montane tropical forest of central Vietnam, Tay Nguyen Plateau, is described based on morphological,molecular, and acoustic evidence. The Golden Bug-Eyed Frog, Theloderma auratum sp. nov., is distinguishable from its congeners and other small rhacophorid species based on a combination of the following morphological attributes:(1) bony ridges on head absent;(2) smooth skin completely lacking calcified warts or asperities;(3) pointed elongated tapering snout;(4) vocal opening in males absent;(5) vomerine teeth absent;(6) males of small body size(SVL 21.8–26.4 mm);(7) head longer than wide;ED/SVL ratio 13%–15%; ESL/SVL ratio 16%–20%;(8)small tympanum(TD/EL ratio 50%–60%) with few tiny tubercles;(9) supratympanic fold absent;(10) ventral surfaces completely smooth;(11) webbing between fingers absent;(12) outer and inner metacarpal tubercles present, supernumerary metacarpal tubercle single, medial, oval in shape;(13) toes half-webbed:Ⅰ 2–2? Ⅱ 1?–2? Ⅲ 2–3? Ⅳ 3–1? Ⅴ;(14) inner metatarsal tubercle present, oval; outer metatarsal tubercle absent;(15) iris bicolored;(16) dorsal surfaces golden-yellow with sparse golden-orange speckling or reticulations and few small dark-brown spots;(17) lateral sides of head and body with wide dark reddish-brown to black lateral stripes, clearlyseparated from lighter dorsal coloration by straight contrasting edge;(18) ventral surfaces of body, throat,and chest greyish-blue with indistinct brown confluent blotches;(19) upper eyelids with few(3–5) very small flat reddish superciliary tubercles;(20) limbs dorsally reddish-brown, ventrally brown with small bluish-white speckles. The new species is also distinct from all congeners in 12 S rRNA to 16 S rRNA mitochondrial DNA fragment sequences(uncorrected genetic distance P>8.9%). Advertisement call and tadpole morphology of the new species are described.Our molecular data showed Theloderma auratum sp. nov. to be a sister species of Th. palliatum from Langbian Plateau in southern Vietnam.
- 宫颈癌组织中ANXA8、PGRMC1和miR-92a表达水平及其与临床病理特征的关系
- 5.0共8页
- 目的 探究宫颈癌患者癌组织中膜联蛋白A8(annexin A8, ANXA8)、孕激素受体膜组分1(progesterone receptor membrane component 1,PGRMC1)以及微小核糖核酸-92a(micro RNA-92a,mi R-92a)的表达及其与临床病理特征的关系。方法 收集2020年1月至2022年3月宜宾市第二人民医院接治的69例宫颈癌患者的宫颈癌和癌旁正常组织69例,采用免疫组织化学法检测ANXA8和PGRMC1阳性率,Western blot检测ANXA8和PGRMC1蛋白表达,RT-PCR法检测ANXA8和PGRMC1 m RNA以及mi R-92a表达水平。此外,分析ANXA8、PGRMC1与mi R-92a表达的线性相关性及其与宫颈癌患者临床病理特征的关系。结果 宫颈癌组织中ANXA8和PGRMC1阳性率(76.81%、72.46%)高于癌旁正常组织(4.35%、7.25%),mi R-92a表达量高于癌旁正常组织(P <0.05)。FIGO分期越高、分化程度越低以及具有淋巴结转移和宫旁浸润,ANXA8和PGRMC1阳性率以及mi R-92a表达量越高(P <0.05)。结论 ANXA8、PGRMC1和mi R-92a在宫颈癌组织中高表达,与宫颈癌肿瘤分期、分化程度、转移和浸润等病理特征有关,可为宫颈癌患者的病理学评估提供可靠依据。
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